Antimicrobial substances produced by Bacillus spp.: innovations for food application

Substâncias antimicrobianas produzidas por Bacillus spp.: inovações para aplicação em alimentos

Authors

  • Vinícius dos Santos Ribeiro State University of Rio Grande do Sul
  • Paula da Silva Pereira Universidade Estadual do Rio Grande do Sul
  • Juliana Oliveira dos Santos State University of Rio Grande do Sul
  • Bibiana Alexandre Federal University of Rio Grande do Sul
  • Fernanda Cortez Lopes Federal University of Rio Grande do Sul
  • Lilian Raquel Hickert State University of Rio Grande do Sul
  • Lúcia Allebrandt da Silva Ries State University of Rio Grande do Sul
  • Patrícia da Silva Malheiros Federal University of Rio Grande do Sul
  • Karla Joseane Perez Universidade Estadual do Rio Grande do Sul

DOI:

https://doi.org/10.4322/2359-6643.13246

Abstract

One of the main challenges faced in the production of food is microbial contamination and spoilage. Due to the increasing consumer demand for safe foods and with low addition of synthetic preservatives, industry is looking for natural and safe alternatives. In this scenario, antimicrobial peptides stand out. Bacillus spp. are considered excellent producers of antimicrobial substances such as bacteriocins, bacteriocin-like substances (BLIS), and lipopeptides. However, these substances face practical and economic obstacles that make their definitive use in the food industry difficult. The present work aims to develop a systematic literature review focused on antimicrobial substances produced by Bacillus spp., as well as new technologies developed with potential use in the food industry and the difficulties faced in their development and application. The search resulted in 175 papers and these were refined based on the selection criteria, resulting in 28 studies included in this systematic review. Nanotechnology and hurdle technology proved to be potential strategies to promote controlled release of active substances, increase the stability of antimicrobial compounds in contact with food matrices and increase the spectrum of action compared to the antimicrobial used alone. In conclusion, the use of antimicrobial peptides produced by Bacillus spp. as natural food preservatives shows great potential, however, it is necessary to optimize production processes when thinking about scaling up for industrial production.

Author Biographies

Vinícius dos Santos Ribeiro, State University of Rio Grande do Sul

Bioprocess and Biotechnology Engineering Student

Paula da Silva Pereira, Universidade Estadual do Rio Grande do Sul

Bioprocess and Biotechnology Engineering Student

Juliana Oliveira dos Santos, State University of Rio Grande do Sul

Bioprocess and Biotechnology Engineering

Bibiana Alexandre, Federal University of Rio Grande do Sul

Food Engineering Student

Fernanda Cortez Lopes, Federal University of Rio Grande do Sul

Pharmacist (Biochemistry), Master and PhD in Cell and Molecular Biology

Lilian Raquel Hickert, State University of Rio Grande do Sul

Assistant professor at UERGS

Lúcia Allebrandt da Silva Ries, State University of Rio Grande do Sul

Assistant professor at UERGS

Patrícia da Silva Malheiros, Federal University of Rio Grande do Sul

Assistant professor at UFRGS

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Published

2023-10-03

Issue

Vol. 13 No. 1 (2023)

Section

Artigo Original

License

Plágio: todos os artigos submetidos passarão por um processo de verificação por meio de software anti-plágio.

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